Anti-INPP4B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-OC-558.50	50 µl		-	-	10 - 15 business days*		206.00€
ABS-OC-558.100	100 µl		-	-	10 - 15 business days*		295.00€

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Protein function: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol... more

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Product information "Anti-INPP4B"

Protein function: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate (PubMed:24070612, PubMed:24591580). Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (PubMed:24591580). The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (PubMed:19647222, PubMed:24070612). [The UniProt Consortium]

Keywords:	Anti-Inositol polyphosphate 4-phosphatase type II, Anti-Type II inositol 3, Anti-4-bisphosphate 4-phosphatase, INPP4B Antibody
Supplier:	Absea
Supplier-Nr:	OC-558

Properties

Application:	IHC
Antibody Type:	Mixed
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human INPP4B
Format:	Solution

Database Information

KEGG ID :	K01109 \| Matching products
UniProt ID :	O15327 \| Matching products
Gene ID :	GeneID 8821 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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