Anti-IMP3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-425A-T	10 µl (2 µg)		-		2 - 8 business days*		165.00€
A303-425A	100 µl		-		2 - 8 business days*		586.00€

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Protein function: RNA-binding factor that may recruits target transcripts to cytoplasmic... more

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Product information "Anti-IMP3"

Protein function: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta- actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. [The UniProt Consortium]

Keywords:	Anti-IMP3, Anti-hKOC, Anti-IMP-3, Anti-IGF2BP3, Anti-VICKZ family member 3, Anti-IGF2 mRNA-binding protein 3, Anti-IGF-II mRNA-binding protein 3, Anti-Insulin-like growth factor 2 mRNA-binding protein 3
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-425A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, chimpanzee, white-tufted-ear marmoset, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-425A-T maps to a region between residue 1 and 50 of human Insulin-Like Growth Factor 2 mRNA Binding Protein 3 using the numbering given in entry NP_006538.2 (GeneID 10643).
Format:	Antigen Affinity Purified