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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
030339.100 | 100 µl | - | - |
3 - 19 business days* |
719.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Integrin-linked kinase (ILK) is an ankyrin repeat-containing serine/threonine protein kinase that... more
Product information "Anti-ILK (Integrin Linked Kinase)"
Integrin-linked kinase (ILK) is an ankyrin repeat-containing serine/threonine protein kinase that interacts with the cytoplasmic domain of Beta-1 and Beta-3 integrins. ILK functions with multiple binding partners to transmit signals from the extracellular matrix to actin filaments, regulating such processes as cellular attachment, cell cycle progression, and cytoskeletal organization. ILK kinase activity is induced by PI3 kinase and negatively regulated by the tumor suppressor PTEN. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. , Applications:, Western Blot: 1:500-1:2000, Immunohistochemistry: 1:200-1:1000, Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-ILK, Anti-ILK1, Anti-ILK-1, Anti-ILK-2, Anti-p59ILK, EC=2.7.11.1, Anti-Integrin-linked protein kinase, Anti-59 kDa serine/threonine-protein kinase |
Supplier: | United States Biological |
Supplier-Nr: | 030339 |
Properties
Application: | ELISA, FC, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 13B417 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, monkey, mouse |
Immunogen: | Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. coli. |
Database Information
KEGG ID : | K06272 | Matching products |
UniProt ID : | Q13418 | Matching products |
Gene ID | GeneID 3611 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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