Anti-ILF3

Anti-ILF3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG57619.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: RNA-binding protein that plays an essential role in the biogenesis of circular... more
Product information "Anti-ILF3"
Protein function: RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back- splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs (PubMed:28625552). As a consequence, participates in a wide range of transcriptional and post-transcriptional processes. Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response (PubMed:21123651). Mechanistically, ILF3 becomes phosphorylated and activated by the double-stranded RNA-activated protein kinase/PKR which releases ILF3 from cellular mature circRNAs. In turn, unbound ILF3 molecules are able to interact with and thus inhibit viral mRNAs (PubMed:21123651, PubMed:28625552). [The UniProt Consortium]
Keywords: Anti-DRBF, Anti-NFAR, Anti-ILF3, Anti-MPP4, Anti-TCP80, Anti-DRBP76, Anti-NF-AT-90, Anti-M-phase phosphoprotein 4, Anti-Translational control protein 80, Anti-Nuclear factor associated with dsRNA, Anti-Interleukin enhancer-binding factor 3
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG57619

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse)
Immunogen: Recombinant protein of Human ILF3
MW: 95 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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