Anti-IL6 (sirukumab biosimilar) mAb, biotinylated

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
DIM-BME100669B.50	50 µg		-	-	7 - 16 business days*		145.00€
DIM-BME100669B.100	100 µg		-	-	7 - 16 business days*		291.00€

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Research use only. Protein function: Cytokine with a wide variety of biological functions in... more

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Product information "Anti-IL6 (sirukumab biosimilar) mAb, biotinylated"

Research use only. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans- signaling'. Alternatively, 'cluster signaling' occurs when membrane- bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). [The UniProt Consortium]

Keywords:	CNTO-136,CNTO136,CNTO 136,PLIVENSIA,Shirukumabu, Anti-CDF, Anti-IL-6, Anti-BSF-2, Anti-IFNB2, Anti-IFN-beta-2, Anti-Interleukin-6, Anti-Interferon beta-2, Anti-Hybridoma growth factor, Anti-CTL differentiation factor, Anti-B-cell stimulatory factor 2
Supplier:	DIMA
Supplier-Nr:	BME100669B

Properties

Antibody Type:	Monoclonal
Conjugate:	Biotin
Species reactivity:	human
Format:	Lyophilized

Database Information

KEGG ID :	K05405 \| Matching products
UniProt ID :	P05231 \| Matching products
Gene ID :	GeneID 3569 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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