Anti-IL4

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin-4, also knowns as a B-cell stimulatory factor 1 (BSF1), is an immunomodulatory cytokine which can inhibit the growth of tumour cells. The protein may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. Protein function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. [The UniProt Consortium]