Anti-IL-4 (equine)

The Equine IL-4 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. The Equine IL-2 polyclonal antibody was produced in goats and is antigen-affinity purified. The reactivity by species is: (Bovine IL-4 - None) (Chicken IL-4 - None) (Equine IL-4 - Strong) (Feline IL-4 - None) (Human IL-4 - None) (Rabbit IL-4 - None) (Swine IL-4 - None). For research use only. Made in the USA Protein function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. [The UniProt Consortium]