Anti-IL-36beta (human), pAb (IN107)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-25B-0032-C100	100 µg		-		3 - 9 business days*		171.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and... more

Close menu

Product information "Anti-IL-36beta (human), pAb (IN107)"

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Keywords:	Anti-IL36B, Anti-IL1F8, Anti-IL-1H2, Anti-IL-1F8, Anti-FIL1 eta, Anti-IL-1 eta, Anti-Interleukin-1 eta, Anti-Interleukin-36 beta, Anti-Interleukin-1 homolog 2, Anti-Interleukin-1 family member 8
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-25B-0032

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Clone:	IN107
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant human IL-36beta
Format:	Purified