Anti-Il-23 receptor / Il23r

Anti-Il-23 receptor / Il23r
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32848 100 µg - -

3 - 10 business days*

790.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin 23 receptor is a type I... more
Product information "Anti-Il-23 receptor / Il23r"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Protein function: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. [The UniProt Consortium]
Keywords: Anti-Il23r, Anti-IL-23R, Anti-IL-23 receptor, Anti-Interleukin-23 receptor, Il-23 receptor Antibody / Il23r
Supplier: NSJ Bioreagents
Supplier-Nr: R32848

Properties

Application: WB, ELISA (capture)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse, rat
Immunogen: A recombinant mouse protein corresponding to amino acids I25-D233 was used as the immunogen for the Il23r antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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