Anti-IL-1RII, Human, mAb 6G5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
HYC-HM2054-20UG	20 µg		-		Request delivery time estimate		139.00€
HYC-HM2054-100UG	100 µg		-		Request delivery time estimate		431.00€

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Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities.... more

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Product information "Anti-IL-1RII, Human, mAb 6G5"

Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Keywords:	Anti-IL1R2, Anti-CDw121b, Anti-IL-1 type II receptor, Anti-Interleukin-1 receptor beta, Anti-Interleukin-1 receptor type 2, Anti-Interleukin-1 receptor type II, Anti-CD121 antigen-like family member B
Supplier:	Hycult Biotech
Supplier-Nr:	HM2054

Properties

Application:	ELISA
Antibody Type:	Monoclonal
Clone:	6G5
Conjugate:	No
Species reactivity:	human
Format:	Sterile Solution

Database Information

KEGG ID :	K04387 \| Matching products
UniProt ID :	P27930 \| Matching products
Gene ID :	GeneID 7850 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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