Anti-IL-1 R2, clone 7D7

Anti-IL-1 R2, clone 7D7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45363.50 50 µg - -

6 - 14 business days*

822.00€
 
Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities.... more
Product information "Anti-IL-1 R2, clone 7D7"
Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. [The UniProt Consortium]
Keywords: Anti-Il1r2, Anti-Il-1r2, Anti-CD121b, Anti-IL-1R-2, Anti-IL-1RT2, Anti-mIL-1R2, Anti-sIL-1R2, Anti-IL-1RT-2, Anti-mIL-1RII, Anti-sIL-1RII, Anti-IL-1R-beta, Anti-IL-1 type II receptor, Anti-Interleukin-1 receptor beta, Anti-Interleukin-1 receptor type 2, A
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45363

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: 7D7
Conjugate: No
Host: Rat
Species reactivity: mouse
Immunogen: Recombinant protein corresponding to extracellular domain of mouse IL-1 R2
MW: 46 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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