Protein function: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta- actin/ACTB and MYC transcripts. [The UniProt Consortium]
Anti-IMP2, Anti-IMP-2, Anti-IGF2BP2, Anti-VICKZ family member 2, Anti-IGF2 mRNA-binding protein 2, Anti-IGF-II mRNA-binding protein 2, Anti-Hepatocellular carcinoma autoantigen p62, Anti-Insulin-like growth factor 2 mRNA-binding protein 2
Human (Expected: Orangutan)
synthetic peptide. The epitope recognized by A303-316A-T maps to a region between residue 150 and 200 of human Insulin-Like Growth Factor 2 mRNA Binding Protein 2 using the numbering given in entry NP_006539.3 (GeneID 10644).