Anti-IFN lambda 2 (Biotin)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG66113.50 50 µg - -

6 - 14 business days*

688.00€
 
Protein function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a... more
Product information "Anti-IFN lambda 2 (Biotin)"
Protein function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. [The UniProt Consortium]
Keywords: Anti-IFNL2, Anti-IL28A, Anti-IL-28A, Anti-IFN-lambda-2, Anti-Interleukin-28A, Anti-Cytokine Zcyto20, Anti-Interferon lambda-2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG66113

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: Biotin
Host: Rabbit
Species reactivity: human
Immunogen: E. coli derived recombinant Human IFN lambda 2.(PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV)
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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