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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-BT2 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-IFIT1 antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-IFIT1"
Anti-IFIT1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. IFIT1 antibody is human, mouse and rat reactive. At least three isoforms of IFIT1 are known to exist. This antibody is predicted to not cross-react with other members of the IFIT protein family. Protein function: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single- stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses. [The UniProt Consortium]
Keywords: | Anti-P56, Anti-G10P1, Anti-IFIT1, Anti-IFIT-1, Anti-IFI-56K, Anti-Interferon-induced 56 kDa protein, Anti-Interferon-induced protein with tetratricopeptide repeats 1 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-BT2 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | 18 amino acid peptide near the C-terminus of human IFIT1. |
Format: | Purified |
Database Information
KEGG ID : | K14217 | Matching products |
UniProt ID : | P09914 | Matching products |
Gene ID | GeneID 3434 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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