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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31017 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Iduronate 2 sulfatase (IDS) is an enzyme... more
Product information "Anti-Iduronate 2 sulfatase"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Iduronate 2 sulfatase (IDS) is an enzyme associated with Hunter syndrome. IDS is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al.(1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al.(1992) and Daniele et al.(1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. IDS is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate 2 sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6sulfatase. Protein function: Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. [The UniProt Consortium]
Keywords: | Anti-IDS, Anti-SIDS, Iduronate 2 sulfatase Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31017 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Amino acid sequence from the C-terminus of human IDS (ELCREGKNLLKHFRFRDLE) |
Format: | Purified |
Database Information
KEGG ID : | K01136 | Matching products |
UniProt ID : | P22304 | Matching products |
Gene ID | GeneID 3423 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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