Anti-IDH1 (R132H), monoclonal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NB-26081	100 µl		-	-	10 - 14 business days*		746.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50%... more

Close menu

Product information "Anti-IDH1 (R132H), monoclonal"

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.

Keywords:	Anti-env, Anti-Envelope protein
Supplier:	NewEast Biosciences
Supplier-Nr:	26081

Properties

Application:	ELISA, WB, IF, IHC
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Mouse
Species reactivity:	vertebrates
Immunogen:	recombinant protein of human IDH1 which includes the mutation of R132H
Format:	Purified