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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ4736 | 100 µl | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The HTRA2 gene... more
Product information "Anti-HTRA2 / Omi, clone EEH-8"
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The HTRA2 gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. [RefSeq] Protein function: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [The UniProt Consortium]
Keywords: | Anti-OMI, Anti-HtrA2, Anti-HTRA2, EC=3.4.21.108, Anti-Serine protease 25, Anti-Serine proteinase OMI, Anti-Omi stress-regulated endoprotease, Anti-Serine protease HTRA2, mitochondrial, Anti-High temperature requirement protein A2, HTRA2 Antibody / Omi |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ4736 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | EEH-8 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A synthetic peptide specific to human HTRA2 / Omi |
Format: | Purified |
Database Information
KEGG ID : | K08669 | Matching products |
UniProt ID : | O43464 | Matching products |
Gene ID | GeneID 27429 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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