Anti-HORMAD2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003074.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Essential for synapsis surveillance during meiotic prophase via the recruitment... more

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Product information "Anti-HORMAD2"

Protein function: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid- pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break- independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 85%

Keywords:	Anti-HORMAD2, Anti-HORMA domain-containing protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003074

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: QLSHCITIHK ASKETVFPSQ ITNEHESLKM VKKLFATSIS CITYLRGLFP ESSYGERHLD DLSLKILRED KKCPGSLHII RWIQGCFDAL EKRYLRMAVL TLYTDPMGSE KVTEMYQFKF KYTK (ATA-APrEST73585)