Anti-HOP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19682.50	50 µl		-	-	10 - 15 business days*		173.00€
ELK-ES19682.100	100 µl		-	-	10 - 15 business days*		290.00€

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Protein function: Atypical homeodomain protein which does not bind DNA and is required to... more

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Product information "Anti-HOP"

Protein function: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Nucleus . Cytoplasm .

Keywords:	Anti-HOD, Anti-HOPX, Anti-Odd homeobox protein 1, Anti-Homeodomain-only protein, Anti-Lung cancer-associated Y protein, Anti-Not expressed in choriocarcinoma protein 1, HOP rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19682

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthesized peptide derived from human HOP AA range: 10-90
Format:	Purified