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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A305-900A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A305-900A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing... more
Product information "Anti-HNRNPQ/R"
Protein function: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation assembles into the GAIT complex which binds to stem loop- containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation, seems not to be essential for GAIT complex function. [The UniProt Consortium]
Keywords: | Anti-HNRPQ, Anti-hnRNP Q, Anti-GRY-RBP, Anti-SYNCRIP, Anti-NS1-associated protein 1, Anti-Heterogeneous nuclear ribonucleoprotein Q, Anti-Glycine- and tyrosine-rich RNA-binding protein, Anti-Synaptotagmin-binding, cytoplasmic RNA-interacting protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A305-900A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse, rat) |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K13160 | Matching products |
UniProt ID : | O60506 | Matching products |
Gene ID | GeneID 10492 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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