Anti-HN1, recombinant antibody

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-RC-16581.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-RC-16581.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578,... more

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Product information "Anti-HN1, recombinant antibody"

Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). [The UniProt Consortium]

Keywords:	Anti-ARM2
Supplier:	Absea
Supplier-Nr:	RC-16581

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	K01_4Q05
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	synthesized peptide derived from human HN1
Format:	Solution

Database Information

UniProt ID :	Q9UK76 \| Matching products
Gene ID :	GeneID 51155 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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