Anti-HN1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA059729.100 100 µl -

7 - 10 business days*

463.00€
 
Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578,... more
Product information "Anti-HN1"
Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 97%
Keywords: Anti-ARM2
Supplier: Atlas Antibodies
Supplier-Nr: HPA059729

Properties

Application: ICC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKS (ATA-APrEST86306)

Database Information

UniProt ID : Q9UK76 | Matching products
Gene ID : GeneID 51155 | Matching products
Protein Atlas Nr. : ENSG00000189159

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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