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The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial... more
Product information "Anti-HMGCL"
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein function: Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. [The UniProt Consortium]
Keywords: | Anti-HL, Anti-HMGCL, EC=4.1.3.4, Anti-HMG-CoA lyase, Anti-3-hydroxy-3-methylglutarate-CoA lyase, Anti-Hydroxymethylglutaryl-CoA lyase, mitochondrial, HMGCL Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-62785 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human HMGCL |
Database Information
KEGG ID : | K01640 | Matching products |
UniProt ID : | P35914 | Matching products |
Gene ID | GeneID 3155 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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