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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG45735.50 | 50 µg | - | - |
10 - 15 business days* |
501.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Multifunctional protein with various roles in different cellular compartments.... more
Product information "Anti-HMGB3 / HMG4"
Protein function: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling. {ECO:0000250, UniProtKB:O54879, ECO:0000250, UniProtKB:P09429, ECO:0000250, UniProtKB:P40618}. [The UniProt Consortium]
| Keywords: | Anti-HMGB3, Anti-HMG2A, Anti-HMG-4, Anti-HMG-4, Anti-HMG-2a, Anti-HMG-2a, Anti-High mobility group protein 4, Anti-High mobility group protein 4, Anti-High mobility group protein B3, Anti-High mobility group protein 2a, Anti-High mobility group protein B3 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG45735 |
Properties
| Application: | FC, ICC, IF, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Synthetic peptide corresponding to N-terminal region of human HMGB3 / HMG4 |
| MW: | 23 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K11296 | Matching products |
| UniProt ID : | O15347 | Matching products |
| Gene ID : | GeneID 3149 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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