Anti-HLA-ABC (MHC I), clone 246-B8.E7

1 mg/ml in sterile PBS, BSA free, sodium azide free. Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. Protein function: Involved in the presentation of foreign antigens to the immune system. [The UniProt Consortium]