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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V2571SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
781.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in sterile PBS, BSA free, sodium azide free. HLA-A, with HLA-B and HLA-C, belongs to... more
Product information "Anti-HLA-A (MHC I), clone 108-2C5"
1 mg/ml in sterile PBS, BSA free, sodium azide free. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This mAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and Aw33). Its epitope maps between aa65-to-aa80 of the alpha1 domain of the HLA-A. This mAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of the alpha1 domain was demonstrated in the formation of an intralocus HLA-A determinant. Protein function: Involved in the presentation of foreign antigens to the immune system. [The UniProt Consortium]
Keywords: | Anti-HLAA, Anti-HLA-A, Anti-MHC class I antigen A*1, Anti-HLA class I histocompatibility antigen, A-1 alpha chain, HLA-A Antibody (MHC I) |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V2571SAF |
Properties
Application: | FC, IF |
Antibody Type: | Monoclonal |
Clone: | 108-2C5 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Normal human peripheral blood lymphocytes |
Format: | Purified |
Database Information
KEGG ID : | K06751 | Matching products |
UniProt ID : | P30443 | Matching products |
Gene ID : | GeneID 3105 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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