Anti-HIP1 / Huntingtin-interacting protein 1, clone AFG-8

Anti-HIP1 / Huntingtin-interacting protein 1, clone AFG-8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4688 100 µl - -

3 - 10 business days*

755.00€
 
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Plays a role in... more
Product information "Anti-HIP1 / Huntingtin-interacting protein 1, clone AFG-8"
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR) -mediated transcription. Protein function: Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126). Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Regulates presynaptic nerve terminal activity. Enhances androgen receptor (AR)- mediated transcription (PubMed:16027218). May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (PubMed:11007801). Binds 3-phosphoinositides (via ENTH domain) (PubMed:14732715). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (PubMed:14732715). May play a functional role in the cell filament networks (PubMed:18790740). May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11007801, PubMed:12163454). [The UniProt Consortium]
Keywords: Anti-HIP1, Anti-HIP-I, Anti-HIP-1, Anti-Huntingtin-interacting protein I, Anti-Huntingtin-interacting protein 1, HIP1 Antibody / Huntingtin-interacting protein 1
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4688

Properties

Application: WB
Antibody Type: Monoclonal
Clone: AFG-8
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A synthetic peptide specific to human HIP1
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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