Anti-HIF-1 beta

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41508.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Required for activity of the Ah (dioxin) receptor. This protein is required for... more

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Product information "Anti-HIF-1 beta"

Protein function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409). [The UniProt Consortium]

Keywords:	Anti-ARNT, Anti-BHLHE2, Anti-bHLHe2, Anti-HIF1-beta, Anti-HIF-1-beta, Anti-ARNT protein, Anti-Hypoxia-inducible factor 1-beta, Anti-Dioxin receptor, nuclear translocator, Anti-Class E basic helix-loop-helix protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41508

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide of Human HIF-1 beta
MW:	87 kD
Format:	Affinity Purified