Anti-Heterochromatin Protein 1alpha (HP-1 alpha)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BR-G01046.100	100 µl		-		10 - 14 business days*		677.00€

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Protein function: Component of heterochromatin that recognizes and binds histone H3 tails... more

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Product information "Anti-Heterochromatin Protein 1alpha (HP-1 alpha)"

Protein function: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. [The UniProt Consortium]

Keywords:	Anti-Hp1a, Anti-Cbx5, Anti-HP1 alpha, Anti-Chromobox protein homolog 5, Anti-Heterochromatin protein 1 homolog alpha
Supplier:	Bertin Bioreagent
Supplier-Nr:	G01046

Properties

Application:	ELISA, WB, IP, ChIP
Antibody Type:	Monoclonal
Clone:	2G9
Conjugate:	No
Host:	Mouse
Species reactivity:	mouse, human
Immunogen:	Recombinant mouse HP1alpha0
Format:	32160702