Anti-HES1, recombinant antibody

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-RC-16998.50	50 µl		-	-	Request delivery time estimate		232.00€
ABS-RC-16998.100	100 µl		-	-	Request delivery time estimate		332.00€

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Protein function: Transcriptional repressor of genes that require a bHLH protein for their... more

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Product information "Anti-HES1, recombinant antibody"

Protein function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'- CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. [The UniProt Consortium]

Keywords:	Anti-hHL, Anti-HES1, Anti-bHLHb39, Anti-BHLHB39, Anti-Hairy homolog, Anti-Hairy-like protein, Anti-Transcription factor HES-1, Anti-Hairy and enhancer of split 1, Anti-Class B basic helix-loop-helix protein 39
Supplier:	Absea
Supplier-Nr:	RC-16998

Properties

Antibody Type:	Monoclonal
Clone:	K01_4U27
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	synthesized peptide derived from human Hes1
Format:	Solution

Database Information

KEGG ID :	K06054 \| Matching products
UniProt ID :	Q14469 \| Matching products
Gene ID :	GeneID 3280 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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