Anti-HEC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41383.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex,... more

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Product information "Anti-HEC1"

Protein function: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108). [The UniProt Consortium]

Keywords:	Anti-HEC, Anti-NDC80, Anti-HsHec1, Anti-Kinetochore protein Hec1, Anti-Kinetochore-associated protein 2, Anti-Kinetochore protein NDC80 homolog, Anti-Highly expressed in cancer protein, Anti-Retinoblastoma-associated protein HEC
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41383

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide derived from Human HEC1
MW:	74 kD
Format:	Affinity Purified