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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30675 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. DNAJA1 (DnaJ homolog subfamily A member... more
Product information "Anti-HDJ2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. DNAJA1 (DnaJ homolog subfamily A member 1), also called DJA1, HSDJ, HSPF4, and HDJ2, is a protein that in humans is encoded by the DNAJA1 gene. The deduced 397-amino acid DNAJA1 protein is 32% identical to E. coli DnaJ, with the highest identity in the N-terminal region. Among the known DNAJ homologs in S. cerevisiae, DNAJA1 is most identical to YDJ1, which may be involved in the transport of certain proteins into the mitochondria and endoplasmic reticulum. Dja1 is expressed in mouse testis and prostate by immunohistochemical analysis and Western blot analysis. Transplantation experiments with fluorescence-tagged spermatogonia into Dja1 -/- mice revealed a primary defect of Sertoli cells in maintaining spermiogenesis at steps 8 and 9. Protein function: Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co- chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202). [The UniProt Consortium]
Keywords: | Anti-HSDJ, Anti-HSJ-2, Anti-DNAJ2, Anti-hDj-2, Anti-DNAJA1, Anti-Human DnaJ protein 2, Anti-Heat shock protein J2, Anti-DnaJ protein homolog 2, Anti-Heat shock 40 kDa protein 4, Anti-DnaJ homolog subfamily A member 1, HDJ2 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30675 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | An amino acid sequence from the C-terminus of human HDJ2 (NQERRRHYNGEAYEDD) was used as the immunogen for this HDJ2 antibody (100% homologous in human, mouse and rat). |
Format: | Purified |
Database Information
KEGG ID : | K09502 | Matching products |
UniProt ID : | P31689 | Matching products |
Gene ID | GeneID 3301 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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