Anti-HDGF / Hepatoma Derived Growth Factor

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Hepatoma-derived growth factor (HDGF), also known as high mobility group protein 1-like 2 (HMG-1L2), is a protein that in humans is encoded by the HDGF gene. This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. And this gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. Protein function: Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. [The UniProt Consortium]