Anti-hCG, Rabbit Monoclonal (RM330)

Recombinant Antibody. This antibody reacts to hCG (human Chorionic Gonadotropin). The antibody recognizes both the native complex and the beta subunit of hCG. Applications: WB, IHC, ELISA. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Human chorionic gonadotropin (hCG) is a placental hormone that stimulates secretion of the pregnancy-sustaining steroid progesterone. hCG is a member of a family of glycoprotein hormones including pituitary hormones lutropin (luteinizing hormone,LH), follitropin (follicle-stimulating hormone, FSH) and thyrotropin (thyroid-stimulating hormone, TSH). Members of this family are all composed of disulfide-rich heterodimers with two dissimilar subunits namely alpha- and beta-subunits. The alpha subunit is common to all the members of the family within a given species. The beta subunits are distinct in each of the horomones and confer the receptor and biological specificity. hCG can be used as a tumor marker, as its beta subunit is secreted by some cancers including seminoma, choriocarcinoma, germ cell tumors, hydatidiform mole, teratoma with elements of choriocarcinoma and islet cell tumor.