Anti-HCG-beta, clone SPM105

Anti-HCG-beta, clone SPM105
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3708SAF-100UG 100 µg - -

3 - 10 business days*

578.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. HCG is a glycoprotein which is secreted in large... more
Product information "Anti-HCG-beta, clone SPM105"
1 mg/ml in 1X PBS, BSA free, sodium azide free. HCG is a glycoprotein which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. hCG mAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Protein function: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role for pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. [The UniProt Consortium]
Keywords: Anti-Choriogonadotropin subunit beta 7, HCG-beta Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3708SAF

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: SPM105
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant hCG beta protein was used as the immunogen for this hCG beta antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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