Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-399A-T 20 µl (2 blots) -

3 - 9 business days*

A301-399A-M 100 µl (10 blots) -

3 - 9 business days*

A301-399A 100 µl (20 µg) -

3 - 9 business days*

Protein function: Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346,... more
Product information "Anti-HCF1"
Protein function: Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346, PubMed:15190068, PubMed:16624878, PubMed:23629655). Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (PubMed:10675337, PubMed:12244100). Coactivator for EGR2 and GABP2 (PubMed:12244100, PubMed:14532282). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together (PubMed:12670868). Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1 (PubMed:20200153). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Recruits KMT2E/MLL5 to E2F1 responsive promoters promoting transcriptional activation and thereby facilitates G1 to S phase transition (PubMed:23629655). [The UniProt Consortium]
Keywords: Anti-HCF1, Anti-HCFC1
Supplier: Bethyl Laboratories
Supplier-Nr: A301-399A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Dog, Horse, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Duckbill Platypus, Tasmanian Devil, White-tufted-ear Marmoset, Dusky Titi Monkey, Olive Baboon, Small-eared Galago, Little Brown Bat)
Immunogen: synthetic peptide. The epitope recognized by A301-399A-T maps to a region between residue 1700 and 1750 of human host cell factor C1 (VP16-accessory protein) using the numbering given in entry NP_005325.2 (GeneID 3054).
Format: Antigen Affinity Purified

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