Anti-HBS1L

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA029729.25	25 µl		-		3 - 8 business days*		330.00€
ATA-HPA029729.100	100 µl		-		3 - 8 business days*		463.00€

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Protein function: Cotranslational quality control factor involved in the No-Go Decay (NGD)... more

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Product information "Anti-HBS1L"

Protein function: Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway (PubMed:21448132). In the presence of ABCE1 and PELO, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes (PubMed:21448132). Together with PELO and in presence of ABCE1, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs, this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway (PubMed:21448132). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 88%

Keywords:	Anti-HBS1, Anti-ERFS, Anti-HBS1L, Anti-HBS1-like protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA029729

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RNVRGYNYDE DFEDDDLYGQ SVEDDYCISP STAAQFIYSR RDKPSVEPVE EYDYEDLKES SNSVSNHQLS GFDQARLYSC LDHMREVLGD AVPDEI (ATA-APrEST77369)