Anti-Hamartin / TSC1 (isoform 1), C-terminal

Anti-Hamartin / TSC1 (isoform 1), C-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63935.100	100 µg		-	-	6 - 14 business days*		871.00€

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Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth... more

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Product information "Anti-Hamartin / TSC1 (isoform 1), C-terminal"

Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. [The UniProt Consortium]

Keywords:	Anti-TSC1, Anti-KIAA0243, Anti-Hamartin, Anti-Tuberous sclerosis 1 protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63935

Properties

Application:	ELISA, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse, rat, canine)
Immunogen:	C-QLHIMDYNETHHEH
Format:	Ammonium Sulfate Precipitated