Anti-H2AX

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-837A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-837A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-837A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... more
Product information "Anti-H2AX"
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. [The UniProt Consortium]
Keywords: Anti-H2AX, Anti-H2AFX, Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X
Supplier: Bethyl Laboratories
Supplier-Nr: A303-837A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human, Mouse (Expected: Rabbit, Rhesus Monkey, Gorilla, Crab-eating Macaque)
Immunogen: synthetic peptide. The epitope recognized by A303-837A-T maps to the C-terminus of human Histone H2AX using the numbering given in entry P16104 (GeneID 3014).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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