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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG45295.50 | 50 µg | - | - |
6 - 14 business days* |
501.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Serine/threonine kinase that plays a key role in M phase by acting as a... more
Product information "Anti-GWL"
Protein function: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation. [The UniProt Consortium]
| Keywords: | Anti-GW, Anti-GW, Anti-GW, Anti-GWL, Anti-GWL, Anti-hGWL, Anti-hGWL, Anti-MASTL, Anti-MAST-L, Anti-MAST-L, Anti-Serine/threonine-protein kinase greatwall, Anti-Serine/threonine-protein kinase greatwall, Anti-Microtubule-associated serine/threonine-protein |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG45295 |
Properties
| Application: | FC, ICC, IF, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant protein containing to human GWL |
| MW: | 97 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K16309 | Matching products |
| UniProt ID : | Q96GX5 | Matching products |
| Gene ID : | GeneID 84930 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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