Anti-GUK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA048587.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA048587.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP... more

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Product information "Anti-GUK1"

Protein function: Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP) (PubMed:31201273). Involved in the cGMP metabolism in photoreceptors. It may also have a role in the survival and growth progression of some tumors (PubMed:31201273). In addition to its physiological role, GUK1 is essential for convert prodrugs used for the treatment of cancers and viral infections into their pharmacologically active metabolites, most notably acyclovir, ganciclovir, and 6-thioguanine and its closely related analog 6-mercaptopurine (PubMed:197968, PubMed:6248551, PubMed:6306664). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 82%

Keywords:	Anti-GMK, Anti-GMP kinase, Anti-Guanylate kinase, Anti-Guanylate kinase 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA048587

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LRPIYISVQP PSLHVLEQRL RQRNTETEES LVKRLAAAQA DMESSKEPGL FDVVIINDSL DQAYAELKEA LSEEIKKAQR TGA (ATA-APrEST76886)