Anti-GTF2I

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-13087.20 20 µl -

7 - 16 business days*

71.00€
E-AB-13087.60 60 µl -

7 - 16 business days*

143.00€
E-AB-13087.120 120 µl -

7 - 16 business days*

238.00€
E-AB-13087.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded... more
Product information "Anti-GTF2I"
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. Protein function: Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C- FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation. [The UniProt Consortium]
Keywords: Anti-SPIN, Anti-GTF2I, Anti-TFII-I, Anti-BAP135, Anti-BAP-135, Anti-GTFII-I, Anti-BTK-associated protein 135, Anti-SRF-Phox1-interacting protein, Anti-General transcription factor II-I, Anti-Bruton tyrosine kinase-associated protein 135, GTF2I Polyclonal
Supplier: Elabscience
Supplier-Nr: E-AB-13087

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human GTF2I
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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