Anti-GSAP

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-KC-2813.50 50 µl - -

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206.00€
ABS-KC-2813.100 100 µl - -

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295.00€
 
Protein function: Regulator of gamma-secretase activity, which specifically activates the... more
Product information "Anti-GSAP"
Protein function: Regulator of gamma-secretase activity, which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42), without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Specifically promotes the gamma- cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta, while it reduces the epsilon-cleavage of APP CTF-alpha, leading to a low production of AICD. [The UniProt Consortium]
Keywords: Anti-Gamma-secretase-activating protein, Anti-GSAP, Anti-Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form, Anti-GSAP-16K], GSAP Antibody
Supplier: Absea
Supplier-Nr: KC-2813

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: 14G1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human GSAP
Format: Solution

Database Information

UniProt ID : A4D1B5 | Matching products
Gene ID : GeneID 54103 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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