Anti-GRP78

Anti-GRP78
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN006780L.25 25 µl -

7 - 16 business days*

110.00€
E-AN006780L.100 100 µl -

7 - 16 business days*

318.00€
 
GRP78 (Glucose-regulated protein 78 kDa, also BiP and HSPA5) is a 72 kDa member of the heat shock... more
Product information "Anti-GRP78"
GRP78 (Glucose-regulated protein 78 kDa, also BiP and HSPA5) is a 72 kDa member of the heat shock protein 70 family of proteins. Intracellularly, GRP78 is an endoplasmic reticulum chaperone that participates in protein folding, extracellularly, it induces IL-10 production from T cells and interacts with Cripto to block TGF-beta signaling. Human GRP78 precursor is 654 amino acids (aa) in length. It contains an 18 aa signal sequence and a 636 aa mature region that shows a hydantoinase A region (aa 145-245) and a C-terminal KDEL motif that is present on intracellular GRP78, but absent on secreted GRP78. There is alternative splicing in the signal sequence (aa 1-10), and multiple single aa substitituion. Over aa 1-654, human GRP78 is more than 97% aa identical to mouse and rat GRP78.
Keywords: Anti-HSPA5, Anti-Binding-immunoglobulin protein, Anti-78 kDa glucose-regulated protein, Anti-Endoplasmic reticulum chaperone BiP, Anti-Heat shock protein family A member 5, Anti-Heat shock protein 70 family protein 5, Anti-Immunoglobulin heavy chain-bindi
Supplier: Elabscience
Supplier-Nr: E-AN006780L

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant Human GRP78 protein expressed by E.coli
MW: 78 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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