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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ4031 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CXCL1 (Chemokine, CXC motif, Ligand 1),... more
Product information "Anti-Gro alpha / CXCL1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CXCL1 (Chemokine, CXC motif, Ligand 1), also called GRO1, SCYB1, GROA or MGSA, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-?). In humans, this protein is encoded by the CXCL1 gene. The CXCL1 gene is mapped on 4q13.3. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. It is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. Signaling through Cxcr2, Cxcl1 inhibited oligodendrocyte precursor migration. The migrational arrest was rapid, reversible, and concentration dependent, and it reflected enhanced cell/substrate interactions. White matter expression of Cxcl1 was temporospatially regulated. Others contribute to aggressive growth selectivity in the lung. Among the lung metastasis signature genes identified, several, including CXCL1, were functionally validated. Protein function: Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation. [The UniProt Consortium]
Keywords: | Anti-Cxcl1, Anti-Cinc1, Anti-CINC-1, Anti-C-X-C motif chemokine 1, Anti-Growth-regulated alpha protein, Anti-Cytokine-induced neutrophil chemoattractant 1, Anti-Platelet-derived growth factor-inducible protein KC, Gro alpha Antibody / CXCL1 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ4031 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse, rat |
Immunogen: | A recombinant rat partial protein corresponding to amino acids A25-K96 was used as the immunogen for the Gro alpha antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05505 | Matching products |
UniProt ID : | P14095 | Matching products |
Gene ID | GeneID 81503 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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