Anti-GRK2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA048330.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA048330.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic... more

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Product information "Anti-GRK2"

Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (PubMed:19715378). Key regulator of LPAR1 signaling (PubMed:19306925). Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (PubMed:19306925). Desensitizes LPAR1 and LPAR2 in a phosphorylation- independent manner (PubMed:19306925). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Inhibits relaxation of airway smooth muscle in response to blue light (PubMed:30284927). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

Keywords:	Anti-ADRBK1, Anti-Beta-ARK-1, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled receptor kinase 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA048330

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LVQWKKELRD AYREAQQLVQ RVPKMKNKPR SPVVELSKVP LVQRGSANGL (ATA-APrEST91140)