Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG55187.50 | 50 µl | - | - |
6 - 14 business days* |
551.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic... more
Product information "Anti-GRK2"
Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (PubMed:19715378). Key regulator of LPAR1 signaling (PubMed:19306925). Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (PubMed:19306925). Desensitizes LPAR1 and LPAR2 in a phosphorylation- independent manner (PubMed:19306925). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Inhibits relaxation of airway smooth muscle in response to blue light (PubMed:30284927). {ECO:0000250, UniProtKB:P21146, ECO:0000269, PubMed:19306925, ECO:0000269, PubMed:19715378, ECO:0000269, PubMed:30284927}. [The UniProt Consortium]
| Keywords: | Anti-ADRBK1, Anti-Beta-ARK-1, Anti-Beta-ARK-1, Anti-Beta-adrenergic receptor kinase 1, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled receptor kinase 2 {ECO:0000312|HGNC:HGNC:289}, Anti-G-protein coupled receptor kinase 2 {ECO:0000312|HGNC |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG55187 |
Properties
| Application: | IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | Recombinant protein of Human GRK2 (NP_001610.2) |
| MW: | 80 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K00910 | Matching products |
| UniProt ID : | P25098 | Matching products |
| Gene ID : | GeneID 156 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed