Anti-Granzyme B, clone SQab1712

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG65858.50	50 µl		-	-	6 - 14 business days*		436.00€

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Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune... more

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Product information "Anti-Granzyme B, clone SQab1712"

Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [The UniProt Consortium]

Keywords:	Anti-HLP, Anti-C11, Anti-SECT, Anti-GZMB, Anti-CGL1, Anti-CTSGL1, Anti-CTLA-1, Anti-Granzyme-2, Anti-Granzyme B, Anti-Fragmentin-2, EC=3.4.21.79, Anti-Cathepsin G-like 1, Anti-Lymphocyte protease, Anti-Human lymphocyte protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG65858

Properties

Application:	IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	SQab1712
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide around aa. 100-200 of Human Granzyme B
MW:	27 kD
Format:	Purified