Anti-GPR83

function:Orphan receptor. Could be a neuropeptide y receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Brain specific., Protein function: G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN (PubMed:27117253). Plays a role in food intake and body weight regulation. May contribute to the regulation of anxiety-related behaviors. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.. Cellular localization: Cell membrane , Multi-pass membrane protein . Colocalizes with GPR171 in the paraventricular nucleus. Colocalizes with the ghrelin receptor GHSR1A in the hypothalamus. .