Anti-GPR52

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA028575.25	25 µl		-		7 - 10 business days*		358.00€
ATA-HPA028575.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an... more

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Product information "Anti-GPR52"

Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 53% and to rat: 53%

Keywords:	Anti-G-protein coupled receptor 52
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA028575

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: CRQHTKEIND RRARFPSHEV DSSRETGHSP DRRYAM (ATA-APrEST77944)